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Cell Development

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Fertilized oocyte day 1. Adjacent and almost centered pronuclei (PN) containing many dispersed nucleoli. Two polar bodies at 11:00. The cytoplasm is retracted with an important halo effect on the right. No laser drilling.
 
Fertilized oocyte day 1. Adjacent and centered pronuclei (PN) containing few dispersed nucleoli. Polar bodies are out of focus. The cytoplasm is retracted with an important halo effect. No laser drilling.

Embryo on day 2. Four equally sized blastomeres
 
Embryo on day 2. Four unequally sized blastomeres

Embryo on day 3. Eight equally sized blastomeres.
 
Extraction of the blastomere. Intermediate phase (blastomere is further extracted).

Embryo on day 4. Morula stage.
 
Embryo on day 4. Morula stage.

Compacting Embryo on day 4.
 
Embryo on day 4. Morula stage.

Early blastocyst on day 4-5. Initiation of a bastocoelic cavity.
 
Early blastocyst on day 4-5. Formation of a clearly visible bastocoelic cavity, zona 19.4µm.

Expanding blastocyst on day 5-6. Inner cell mass visible in the lower portion. Zona thickness between 4.9 µm and 8.2 µm.
 
Expanding blastocyst on day 5-6. Zona thickness between 3.7 µm and 4.7 µm.

Images: Courtesy Dr. Alfred Senn University Hospital (CHUV) Lausanne, Switzerland.

 


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